Thymic Hyperplasia as a Source of Ectopic ACTH Production.
نویسندگان
چکیده
منابع مشابه
Thymic hyperplasia as a source of ectopic ACTH production.
A 26 year-old man with suspected Cushing's disease underwent transsphenoidal exploration of the pituitary without any evidence of microadenoma or hyperplasia. Progressive hypercortisolism necessitated bilateral adrenalectomy. Postoperatively, skin pigmentation gradually developed with a marked elevation of plasma ACTH levels, and CT scanning uncovered a thymic mass. Following removal of the thy...
متن کاملEctopic ACTH syndrome caused by desmopressin-responsive thymic neuroendocrine tumor.
A 32-year-old Chinese woman with rapid weight gain and progressive edema was found to have typical Cushingoid features. Her endocrine data were consistent with a diagnosis of ACTH-dependent Cushing's syndrome. To differentiate ectopic ACTH syndrome (EAS) from Cushing's disease (CD), various dynamic endocrine and imaging tests were performed. Her ACTH response was negative to corticotropin-relea...
متن کاملEctopic ACTH Production: Diagnosis, Treatment and Prognosis
A 69-year-old woman presented with a four-week history of facial and bilateral leg swelling. She also described symptoms of proximal myopathy. Her past medical history included osteoporosis and osteoarthritis. Routine medication was a weekly bisphosphonate, aspirin and St John’s Wort. Clinical examination identified bilateral pitting oedema to the knees and Cushingoid facies. Her blood pressure...
متن کاملA case report of metastatic atypical thymic carcinoid with ectopic ACTH production: locoregional control after adaptive radiation treatment.
Thymic carcinoid is an extremely rare malignancy. This tumor is often associated with endocrine disorders such as Cushing's syndrome, multiple endocrine neoplasia type 1 and superior vena cava syndrome. We describe the case of a 44-year-old Italian woman with metastatic atypical thymic carcinoid secreting ectopic adrenocorticotropic hormone who was treated with adaptive radiation therapy with a...
متن کاملAtypical Carcinoid Tumor with Ectopic ACTH Production used as a Biochemical Marker of Recurrence
Bronchopulmonary carcinoids, including typical and atypical histologies, are uncommon neuroendocrine tumors that have a wide range of clinical phenotypes. In addition to the carcinoid syndrome, other paraneoplastic syndromes are welldescribed, including ectopic adrenocorticotropic hormone (ACTH) production. The authors describe a case presentation of a 23 year-old man with ectopic ACTH producti...
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ژورنال
عنوان ژورنال: Endocrine Journal
سال: 2000
ISSN: 0918-8959,1348-4540
DOI: 10.1507/endocrj.47.487